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Circulating free insulin-like growth factor-I and prostate cancer: a case-control study nested in the European prospective investigation into cancer and nutrition

Abstract Background Circulating total insulin-like growth factor-I (IGF-I) is an established risk factor for prostate cancer. However, only a small proportion of circulating IGF-I is free or readily dissociable from IGF-binding proteins (its bioavailable form), and few studies have investigated the...

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Principais autores: Tuck Seng Cheng, Urwah Noor, Eleanor Watts, Michael Pollak, Ye Wang, James McKay, Joshua Atkins, Giovanna Masala, Maria-Jose Sánchez, Antonio Agudo, Jesús Castilla, Dagfinn Aune, Sandra M. Colorado-Yohar, Luca Manfredi, Marc J. Gunter, Valeria Pala, Andreas Josefsson, Timothy J. Key, Karl Smith-Byrne, Ruth C. Travis
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-06-01
Serier:BMC Cancer
Fag:
Free IGF-1
Prostate cancer
Histological grade
Tumor stage
Aggressiveness
Online adgang:https://doi.org/10.1186/s12885-023-11425-w
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