Design, synthesis, and anticancer activity of phenoxyacetohydrazide derivatives in burkitt lymphoma

Abstract Burkitt lymphoma (BL) is an aggressive non- Hodgkin lymphoma mainly driven by c- MYC translocations, leading to uncontrolled cell growth and high mortality. Although treatments have improved, issues like toxicity, resistance, and poor outcomes after recurrence remain major challenges. In th...

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Principais autores:	Yasser Hussein Issa Mohammed, Saad Alghamdi, Hibah Ali Almasmoum, Ahmed Hassen Shntaif, Nida Suhail, Bodour S. Rajab, Sadeq K. Alhag, Mariah N. Hafiz, Mohammed M. Jawad, Ahmed M. Senan
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2026-05-01
Series:	Scientific Reports
Assuntos:	Burkitt lymphoma Hydrazide derivatives Anti-tumor activity Cytotoxicity IC50 values Murine model
Acceso en liña:	https://doi.org/10.1038/s41598-026-52968-9
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