Circular Network of Coregulated Sphingolipids Dictates Chronic Hypoxia Damage in Patients With Tetralogy of Fallot

Background: Tetralogy of Fallot (TOF) is the most common cyanotic heart disease. However, the association of cardiac metabolic reprogramming changes and underlying molecular mechanisms in TOF-related chronic myocardial hypoxia damage are still unclear.Methods: In this study, we combined microarray t...

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Bibliographic Details

Main Authors:	Na Zhou, Libao Liu, Rongjun Zou, Minghui Zou, Mingxia Zhang, Fan Cao, Wenhua Liu, Huili Yuan, Guodong Huang, Li Ma, Xinxin Chen
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2022-01-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	Tetralogy of Fallot sphingolipid metabolism metabolomic analysis mass spectrometry analysis cyanotic congenital heart disease
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2021.780123/full
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