Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix

The range of biological outcomes generated by many signalling proteins in development and homeostasis is increased by their interactions with glycosaminoglycans, particularly heparan sulfate (HS). This interaction controls the localization and movement of these signalling proteins, but whether such...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Changye Sun, Marco Marcello, Yong Li, David Mason, Raphaël Lévy, David G. Fernig
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	The Royal Society 2016-01-01
Schriftenreihe:	Open Biology
Schlagworte:	glycosaminoglycan heparan sulfate fibroblast growth factor extracellular matrix growth factor diffusion
Online-Zugang:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150277
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