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Molecular determinants for brain targeting by peptides: a meta-analysis approach with experimental validation

Abstract Blood–brain barrier (BBB) peptide-shuttles (BBBpS) are able to translocate the BBB and reach the brain. Despite the importance of brain targeting in pharmacology, BBBpS are poorly characterized. Currently, their development relies on the empiric assumption that cell-penetrating peptides (CP...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Marco Cavaco, Patrícia Fraga, Javier Valle, Ruben D. M. Silva, Lurdes Gano, João D. G. Correia, David Andreu, Miguel A. R. B. Castanho, Vera Neves
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2024-05-01
Rangatū:Fluids and Barriers of the CNS
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12987-024-00545-5
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