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Impact of structural modifications of IgG antibodies on effector functions

Immunoglobulin G (IgG) antibodies are a critical component of the adaptive immune system, binding to and neutralizing pathogens and other foreign substances. Recent advances in molecular antibody biology and structural protein engineering enabled the modification of IgG antibodies to enhance their t...

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Autores principales: Timon Damelang, Maximilian Brinkhaus, Thijs L. J. van Osch, Janine Schuurman, Aran F. Labrijn, Theo Rispens, Gestur Vidarsson
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2024-01-01
Colección:Frontiers in Immunology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1304365/full
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