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P-glycoprotein dysfunction contributes to hepatic steatosis and obesity in mice.

Although the main role of P-glycoprotein (Pgp) is to extrude a broad range of xenochemicals and to protect the organism against xenotoxicity, it also transports a large range of endogenous lipids. Using mice lacking Pgp, we have investigated the possible involvement of Pgp in lipid homeostasis in vi...

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書誌詳細
主要な著者: Magali Foucaud-Vignault, Zeina Soayfane, Cécile Ménez, Justine Bertrand-Michel, Pascal Guy Pierre Martin, Hervé Guillou, Xavier Collet, Anne Lespine
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2011-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023614&type=printable
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