Effects of Loperamide on Mechanical Allodynia Induced by Herpes Simplex Virus Type-1 in Mice
In the present study, we investigated whether the peripherally acting µ-opioid receptor agonist loperamide would inhibit allodynia in the non-inflamed dermatome of mice with herpetic pain. Subcutaneous (s.c.) injection of loperamide (1 and 3 mg/kg) inhibited allodynia. Local (intraplantar) injection...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2007-01-01
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| Col·lecció: | Journal of Pharmacological Sciences |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S134786131934246X |
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