α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Abstract Understanding the progression of α‐synuclein pathology in neurodegenerative diseases such as Parkinson's disease (PD) is a longstanding challenge. Here, a novel midbrain–hindbrain‐assembloid model that recapitulates the spread of α‐synuclein pathology observed in PD patients, akin to Braak'...

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Bibliografiske detaljer

Principais autores:	Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielmann, Regina Luttge, Jens C. Schwamborn
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2025-05-01
Serier:	Advanced Science
Fag:	α‐synuclein brain organoid in vitro disease modeling Parkinson's disease
Online adgang:	https://doi.org/10.1002/advs.202409040
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