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Delivery of Berberine Using Chitosan/Fucoidan-Taurine Conjugate Nanoparticles for Treatment of Defective Intestinal Epithelial Tight Junction Barrier

Bacterial-derived lipopolysaccharides (LPS) can cause defective intestinal barrier function and play an important role in the development of inflammatory bowel disease. In this study, a nanocarrier based on chitosan and fucoidan was developed for oral delivery of berberine (Ber). A sulfonated fucoid...

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Sparad:
Huvudupphov: Shao-Jung Wu, Trong-Ming Don, Cheng-Wei Lin, Fwu-Long Mi
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2014-11-01
Serie:Marine Drugs
Ämnen:
chitosan
fucoidan
nanoparticles
drug delivery
tight junction
Länkar:http://www.mdpi.com/1660-3397/12/11/5677
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