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Expression of the Transcription Factor Egr-1 in Pancreatic Acinar Cells Following Stimulation of Cholecystokinin or Gαq-Coupled Designer Receptors

Backgound/Aims: The injection of cerulein, an analogue of the pancreatic secretagogue cholecystokinin (CCK), induces acute pancreatitis in mice that is accompanied by the synthesis of the transcription factor Egr-1. The signaling cascade that connects cerulein stimulation with enhanced Egr-1 biosynt...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Anke Kaufmann, Oliver G. Rössler, Gerald Thiel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
Schriftenreihe:Cellular Physiology and Biochemistry
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Online-Zugang:http://www.karger.com/Article/FullText/358707
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