The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles

RNA vaccines are applicable to the treatment of various infectious diseases via the inducement of robust immune responses against target antigens by expressing antigen proteins in the human body. The delivery of messenger RNA by lipid nanoparticles (LNPs) has become a versatile drug delivery system...

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Autors principals:	Jessica Anindita, Hiroki Tanaka, Takuma Yamakawa, Yuka Sato, Chika Matsumoto, Kota Ishizaki, Taiji Oyama, Satoko Suzuki, Keisuke Ueda, Kenjirou Higashi, Kunikazu Moribe, Kasumi Sasaki, Yumika Ogura, Etsuo Yonemochi, Yu Sakurai, Hiroto Hatakeyama, Hidetaka Akita
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-01-01
Col·lecció:	Pharmaceutics
Matèries:	lipid nanoparticle cholesterol particle morphology adjuvant activity
Accés en línia:	https://www.mdpi.com/1999-4923/16/2/181
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