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VGSC-DB: an online database of voltage-gated sodium channels

Abstract As an important member of ion channels family, the voltage-gated sodium channel (VGSC/Nav) is associated with a variety of diseases, including epilepsy, migraine, ataxia, etc., and has always been a hot target for drug design and discovery. Many subtype-selective modulators targeting VGSCs...

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Principais autores: Gaoang Wang, Jiahui Yu, Hongyan Du, Chao Shen, Xujun Zhang, Yifei Liu, Yangyang Zhang, Dongsheng Cao, Peichen Pan, Tingjun Hou
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-11-01
coleção:Journal of Cheminformatics
Assuntos:
Voltage-gated sodium channels
VGSC-DB
Drug discovery
Open-source database
Computer-aided drug design
Acesso em linha:https://doi.org/10.1186/s13321-022-00655-y
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