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Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats

<p>Abstract</p> <p>Background</p> <p>Mast cells (MCs) are implicated in inflammation and tissue remodeling. Accumulation of lung MCs is described in pulmonary hypertension (PH); however, whether MC degranulation and c-kit, a tyrosine kinase receptor critically involved in MC biology, contribute to t...

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Detalhes bibliográficos
Principais autores: Ghofrani Hossein A, Reiss Irwin, Hoffmann Julia, Savai Rajkumar, Cornitescu Teodora, Kaulen Christina, Kosanovic Djuro, Dahal Bhola K, Weissmann Norbert, Kuebler Wolfgang M, Seeger Werner, Grimminger Friedrich, Schermuly Ralph T
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2011-05-01
Colecção:Respiratory Research
Acesso em linha:http://respiratory-research.com/content/12/1/60
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