Metabolic reprogramming orchestrates microglial fate in cerebral ischemia-reperfusion injury: a spatiotemporal immunometabolic perspective

Cerebral ischemia-reperfusion injury (CIRI) represents a critical pathological cascade that paradoxically exacerbates neurological damage following revascularization therapy for acute ischemic stroke (AIS). The pathogenesis of CIRI is intricately linked to dysregulated neuroinflammation, with microg...

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Dades bibliogràfiques

Autors principals:	Meng Zhang, Huimin Li, Wei Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-07-01
Col·lecció:	Frontiers in Immunology
Matèries:	cerebral ischemia-reperfusion injury immunometabolism metabolic reprogramming microglia neuroinflammation redox signaling
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1831494/full
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