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The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway.

Insulin/insulin-like growth factor signaling (IIS) plays a pivotal role in the regulation of growth at the cellular and the organismal level during animal development. Flies with impaired IIS are developmentally delayed and small due to fewer and smaller cells. In the search for new growth-promoting...

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Autors principals: Christian Werz, Katja Köhler, Ernst Hafen, Hugo Stocker
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2009-08-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC2716533?pdf=render
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