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Combination of cadonilimab (PD-1/CTLA-4 bispecific antibody) and apatinib as salvage therapy achieves partial response in MSI-H advanced gastric cancer: a case report

Microsatellite instability-high (MSI-H) gastric cancer (GC) is recognized as a unique subtype of gastric cancer. While patients with advanced MSI-H gastric cancer may respond favorably to a combination of immune checkpoint inhibitors and chemotherapy in first-line treatment, no definitive recommenda...

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Principais autores: Jiayu Zhao, Xiaoxiao Li, Xiaoyuan Sun, Ruoxi Xiao, Juan Xue, Kexin Sui, Zimin Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-02-01
coleção:Frontiers in Immunology
Assuntos:
PD-1/CTLA-4 bispecific antibody
AK104/cadonilimab
microsatellite instability
apatinib
salvage therapy
advanced gastric cancer
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1533700/full
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