PPARα Agonist, MHY3200, Alleviates Renal Inflammation during Aging via Regulating ROS/Akt/FoxO1 Signaling

PPARα is a ligand-dependent transcription factor and its activation is known to play an important role in cell defense through anti-inflammatory and antioxidant effects. MHY3200 (2-[4-(5-chlorobenzo[<i>d</i>]thiazol-2-yl)phenoxy]-2,2-difluoroacetic acid), a novel benzothiazole-derived peroxisome pro...

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Bibliografski detalji

Glavni autori:	Min Jo Kim, Dae Hyun Kim, EunJin Bang, Sang Gyun Noh, Pusoon Chun, Takako Yokozawa, Hyung Ryong Moon, Hae Young Chung
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-05-01
Serija:	Molecules
Teme:	aging MHY3200 ROS Akt NF-κB inflammation
Online pristup:	https://www.mdpi.com/1420-3049/26/11/3197
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