3,5-Diiodo-L-Thyronine Affects Structural and Metabolic Features of Skeletal Muscle Mitochondria in High-Fat-Diet Fed Rats Producing a Co-adaptation to the Glycolytic Fiber Phenotype

Hyperlipidemic state-associated perturbations in the network of factors controlling mitochondrial functions, i. e., morphogenesis machinery and metabolic sensor proteins, produce metabolic inflexibility, insulin resistance and reduced oxidative capacity in skeletal muscle. Moreover, intramyocellular...

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Detalhes bibliográficos

Principais autores:	Elena Silvestri, Federica Cioffi, Rita De Matteis, Rosalba Senese, Pieter de Lange, Maria Coppola, Anna M. Salzano, Andrea Scaloni, Michele Ceccarelli, Fernando Goglia, Antonia Lanni, Maria Moreno, Assunta Lombardi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-03-01
coleção:	Frontiers in Physiology
Assuntos:	skeletal muscle proteomics mitochondrion diiodothyronine reactive oxygen species inflammation
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fphys.2018.00194/full
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