Preparation, Characterization, and In Vivo Evaluation of an Oral Triptolide Nanomatrix System for Rheumatoid Arthritis Therapy

<b>Background</b>: Triptolide (TP), a principal bioactive component of <i>Tripterygium wilfordii</i>, exhibits potent anti-inflammatory activity. However, its application is still limited due to its poor solubility and systemic toxicity, primarily caused by uncontrolled absorption after oral adminis...

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Autors principals:	Yujian Liang, Mingyu Li, Qing Zhou, Chenyang Liu, Longfei Lin, Liuqing Yang, Wenbing Dai
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-12-01
Col·lecció:	Pharmaceutics
Matèries:	triptolide solid nanomatrix rheumatoid arthritis dissolution behavior Eudragit<sup>®</sup>
Accés en línia:	https://www.mdpi.com/1999-4923/17/12/1567
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