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Causal association between 1400 metabolites and dilated cardiomyopathy: a bidirectional two-sample Mendelian randomization analysis

BackgroundDilated cardiomyopathy (DCM) is a cardiac disease with a poor prognosis of unclear etiology. Previous studies have shown that metabolism is associated with DCM. This study investigates the causal relationship between 1400 metabolites and DCM using a two-sample Mendelian randomization (MR)...

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Główni autorzy: Xianghui Zeng, Qingfeng Zeng, Xianggui Wang, Kening Li, Jincheng Wu, Jianping Luo
Format: Artigo
Język:Inglês
Wydane: Frontiers Media S.A. 2024-09-01
Seria:Frontiers in Endocrinology
Hasła przedmiotowe:
dilated cardiomyopathy
metabolites
Mendelian randomization
causal analysis
genetic variants
epidemiology
Dostęp online:https://www.frontiersin.org/articles/10.3389/fendo.2024.1423142/full
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