Apelin, Cortisol, and Doxorubicin-Induced Cardiotoxicity: A Triangle of Actions
The mechanisms underlying doxorubicin (DOX) cardiotoxicity include activation of the renin–angiotensin–aldosterone system (RAAS), oxidative stress, mitochondrial dysfunction, calcium overload, and cardiomyocyte apoptosis. Cortisol plays a key role in regulating multiple metabolic, immunological, car...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2026-06-01
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| Series: | Cells |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/2073-4409/15/13/1187 |
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