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Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest

 The histone methyltransferase Polycomb repressive complex 2 (PRC2) is required for specification of the neural crest, and mis-regulation of neural crest development can cause severe congenital malformations. PRC2 is necessary for neural crest induction, but the embryonic, cellular, and molecular co...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Tim Casey-Clyde, S John Liu, Angelo Pelonero, Juan Antonio Camara Serrano, Camilla Teng, Yoon-Gu Jang, Harish N Vasudevan, Arun Padmanabhan, Jeffrey Ohmann Bush, David R Raleigh
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2025-12-01
Schriftenreihe:eLife
Schlagworte:
craniofacial development
single-cell sequencing
chromatin
epigenetics
osteoblasts
mesenchymal
Online-Zugang:https://elifesciences.org/articles/100159
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