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Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults.

Loci identified in genome-wide association studies (GWAS) of cardio-metabolic traits account for a small proportion of the traits' heritability. To date, most association studies have not considered parent-of-origin effects (POEs). Here we report investigation of POEs on adiposity and glycemic trait...

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Autors principals: Hagit Hochner, Catherine Allard, Einat Granot-Hershkovitz, Jinbo Chen, Colleen M Sitlani, Sandra Sazdovska, Thomas Lumley, Barbara McKnight, Kenneth Rice, Daniel A Enquobahrie, James B Meigs, Pui Kwok, Marie-France Hivert, Ingrid B Borecki, Felicia Gomez, Ting Wang, Cornelia van Duijn, Najaf Amin, Jerome I Rotter, John Stamatoyannopoulos, Vardiella Meiner, Orly Manor, Josée Dupuis, Yechiel Friedlander, David S Siscovick
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-10-01
Col·lecció:PLoS Genetics
Accés en línia:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005573&type=printable
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