Rewiring of 3D chromatin topology orchestrates transcriptional reprogramming in muscle fiber-type specification and transformation
Abstract The composition of muscle fibers, characterized by distinct contractile and metabolic properties, significantly influences meat quality and glucose homeostasis. However, the mechanisms by which three-dimensional (3D) genome topology integrates with epigenetic states to regulate muscle fiber...
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| Principais autores: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Portfolio
2025-07-01
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| 叢編: | Nature Communications |
| 在線閱讀: | https://doi.org/10.1038/s41467-025-60866-3 |
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