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Experimental murine acute lung injury induces increase of pulmonary TIE2-expressing macrophages

Abstract Background Breakdown of the alveolo-capillary wall is pathognomonic for Acute Lung Injury (ALI). Angiopoietins, vascular-specific growth factors, are linked to endothelial barrier dysfunction, and elevated Angiopoietin-2 (ANG2) levels are associated with poor outcome of ALI patients. Specia...

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Principais autores: Heidi Ehrentraut, Christina Weisheit, Marcel Scheck, Stilla Frede, Tobias Hilbert
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-06-01
Series:Journal of Inflammation
Assuntos:
Acute lung injury
Inflammation
TIE2
Monocytes
Macrophages
Angiopoietin
Acceso en liña:http://link.springer.com/article/10.1186/s12950-018-0188-5
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