Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice
Vascular aging affects multiple organ systems, including the brain, where it can lead to vascular dementia. However, a concrete understanding of how aging specifically affects the brain vasculature, along with molecular readouts, remains vastly incomplete. Here, we demonstrate that aging is associat...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2024-01-01
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| Seria: | The Journal of Clinical Investigation |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1172/JCI166134 |
| Etykiety: |
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