<i>Atractylodes lancea</i> (Thunb.) DC. [Asteraceae] Rhizome-Derived Exosome-like Nanoparticles Suppress Lipopolysaccharide-Induced Inflammation by Reducing Toll-like Receptor 4 Expression in BV-2 Murine Microglial Cells

<b>Background/Objectives:</b> <i>Atractylodes lancea</i> (Thunb.) DC. [Asteraceae] (ALR)-derived exosome-like nanoparticles (ALR-ELNs) exhibit anti-neuroinflammatory effects in microglial cells. However, the associated mechanisms and pathways are unknown. We aimed to characterize the effects of ALR-...

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Autors principals:	Mizusa Hyodo, Kei Kawada, Tomoaki Ishida, Yuki Izawa-Ishizawa, Ryoko Matoba, Rina Okamoto, Kohei Jobu, Io Horikawa, Fuka Aizawa, Kenta Yagi, Takahiro Niimura, Yayoi Kawano, Shinji Abe, Yukihiro Hamada, Mitsuhiro Goda, Keisuke Ishizawa
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-07-01
Col·lecció:	Pharmaceuticals
Matèries:	<i>Atractylodes lancea</i> rhizome microglia exosome-like nanoparticle neuroinflammation RNA sequencing ingenuity pathway analysis
Accés en línia:	https://www.mdpi.com/1424-8247/18/8/1099
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