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14-3-3σ gene silencing during melanoma progression and its role in cell cycle control and cellular senescence

<p>Abstract</p> <p>Background</p> <p>The family of 14-3-3 proteins plays an important role in cancer biology by interfering with intracellular signalling pathways and cell cycle checkpoints. The 14-3-3σ isoform acts as a tumor suppressor and is often inactivated during tumor development.</p> <p>Resu...

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Principais autores: Vera Julio, Ibrahim Saleh M, Schultz Julia, Kunz Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2009-07-01
coleção:Molecular Cancer
Acesso em linha:http://www.molecular-cancer.com/content/8/1/53
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