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Various Tastes of Sugar: The Potential of Glycosylation in Targeting and Modulating Human Immunity via C-Type Lectin Receptors

C-type lectin receptors (CLRs) are important in several immune regulatory processes. These receptors recognize glycans expressed by host cells or by pathogens. Whereas pathogens are recognized through their glycans, which leads to protective immunity, aberrant cellular glycans are now increasingly r...

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Автори: Stefanie Busold, Noémi A. Nagy, Sander W. Tas, Ronald van Ree, Esther C. de Jong, Teunis B. H. Geijtenbeek
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2020-02-01
Серія:Frontiers in Immunology
Предмети:
protein glycosylation in immunology
C-type lectin receptors
in vivo targeting dendritic cells
immunotherapy
immunomodulation
glycan vaccines
Онлайн доступ:https://www.frontiersin.org/article/10.3389/fimmu.2020.00134/full
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