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The Effect of Resistance Training and Ursolic Acid on the PI3K‐AKT‐mTOR Pathway in Aged Diabetic Rats: A Comparative Study

ABSTRACT Objectives Sarcopenia, characterized by age‐related muscle loss, worsens in diabetes due to anabolic resistance. Ursolic acid (UA), a natural compound with anabolic and anti‐catabolic effects, may mitigate sarcopenia by enhancing anabolic pathways. This study examined the effects of 8 weeks...

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Principais autores: Ashkan Sadeghi, Safoura Alizade, Mohammad Faramarzi, Mostafa Rahimi, Rohit Kumar Thapa
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-06-01
Serier:Aging Medicine
Fag:
glucose metabolism disorders
insulin resistance
muscle atrophy
sarcopenia
type 2 diabetes mellitus
Online adgang:https://doi.org/10.1002/agm2.70071
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