Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases

ABSTRACT Carboxyl (C)-terminal processing proteases (CTPs) participate in protective and regulatory proteolysis in bacteria. The PDZ domain is central to the activity of CTPs but plays inherently different regulatory roles. For example, the PDZ domain inhibits the activity of the signaling protease...

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Detalles Bibliográficos

Principais autores:	Chuang-Kai Chueh, Nilanjan Som, Lu-Chu Ke, Meng-Ru Ho, Manjula Reddy, Chung-I Chang
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2019-08-01
Series:	mBio
Assuntos:	PDZ domain enzyme activation mechanisms of action proteases CTP Prc
Acceso en liña:	https://journals.asm.org/doi/10.1128/mBio.01129-19
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