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Unveiling the mechanisms of neuropathic pain suppression: perineural resiniferatoxin targets Trpv1 and beyond

Neuropathic pain arises from damage or disorders affecting the somatosensory system. In rats, L5 nerve injury induces thermal and mechanical hypersensitivity/hyperalgesia. Recently, we demonstrated that applying resiniferatoxin (RTX) directly on uninjured L3 and L4 nerves alleviated thermal and mech...

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Библиографические подробности
Главные авторы: Safa Shehab, Hayate Javed, Aishwarya Mary Johnson, Saeed Tariq, Challagandla Anil Kumar, Bright Starling Emerald
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2023-11-01
Серии:Frontiers in Neuroanatomy
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fnana.2023.1306180/full
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