Oxymatrine Inhibits Renal Tubular EMT Induced by High Glucose via Upregulation of SnoN and Inhibition of TGF-β1/Smad Signaling Pathway.

Transforming growth factor-β1 (TGF-β1) signaling has been shown to play a critical role in the development of diabetic nephropathy (DN). The nuclear transcription co-repressor Ski-related novel protein N (SnoN) is an important negative regulator of TGF-β1/Smad signal transduction, and subsequent bio...

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主要な著者:	Lirong Liu, Yuanyuan Wang, Rui Yan, Shuang Li, Mingjun Shi, Ying Xiao, Bing Guo
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2016-01-01
シリーズ:	PLoS ONE
オンライン･アクセス:	https://doi.org/10.1371/journal.pone.0151986
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