Exploring the epigenetic modifications of the RONS-TRPA1-CGRP axis in migraine pathophysiology

Abstract Background Epigenetic studies in migraine provided results on the occurrence or lack of epigenetic modifications of genes whose products are important in migraine pathogenesis. However, these studies focus on single genes without analyzing how epigenetic modifications can affect complex sig...

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Detalhes bibliográficos

Principais autores:	Michal Fila, Elzbieta Pawlowska, Jan Krekora, Maria Mitus-Kenig, Janusz Blasiak
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-09-01
coleção:	The Journal of Headache and Pain
Assuntos:	Migraine Epigenetics Reactive oxygen and nitrogen species TRPA1 CGRP Oxidative stress
Acesso em linha:	https://doi.org/10.1186/s10194-025-02114-z
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