Insulin levels at 18–20 gestational weeks in pregnant women with obesity are associated with newborn abdominal fat deposition and DNA methylation in cord blood

Abstract We assessed if fasting plasma insulin levels in pregnant women with obesity are associated with newborns’ abdominal fat deposition (dual-energy X-ray absorptiometry) and with cord blood DNA methylation (450k array) in 232 mother–child pairs from the Treatment of Obese Pregnant women (TOP) s...

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Autores principales:	Alice Maguolo, Josefine Jönsson, Alexander Perfilyev, Allan Vaag, Emma Malchau Carlsen, Kirsten Nørgaard, Paul W. Franks, Kristina M. Renault, Charlotte Ling
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-07-01
Colección:	Clinical Epigenetics
Materias:	Epigenetics DNA methylation Diabetes Fetal programming Early life Maternal insulin
Acceso en línea:	https://doi.org/10.1186/s13148-025-01923-y
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