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Hyperpiliation, not loss of pilus retraction, reduces Pseudomonas aeruginosa pathogenicity

ABSTRACT Type IVa pili (T4aP) are important virulence factors for many bacterial pathogens. Previous studies suggested that the retraction ATPase, PilT, modulates pathogenicity due to its critical role in pilus dynamics and twitching motility. Here we use a Caenorhabditis elegans slow-killing model...

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Bibliografische gegevens
Hoofdauteurs: Sara L. N. Kilmury, Katherine J. Graham, Ryan P. Lamers, Lesley T. MacNeil, Lori L. Burrows
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2025-04-01
Reeks:Microbiology Spectrum
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Online toegang:https://journals.asm.org/doi/10.1128/spectrum.02558-24
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