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Sleep fragmentation after traumatic brain injury impairs behavior and conveys long-lasting impacts on neuroinflammation

Traumatic brain injury (TBI) causes a prolonged inflammatory response in the central nervous system (CNS) driven by microglia. Microglial reactivity is exacerbated by stress, which often provokes sleep disturbances. We have previously shown that sleep fragmentation (SF) stress after experimental TBI...

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Principais autores: Samuel Houle, Zoe Tapp, Shannon Dobres, Sakeef Ahsan, Yvanna Reyes, Christopher Cotter, Jessica Mitsch, Zachary Zimomra, Juan Peng, Rachel K. Rowe, Jonathan Lifshitz, John Sheridan, Jonathan Godbout, Olga N. Kokiko-Cochran
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-07-01
coleção:Brain, Behavior, & Immunity - Health
Assuntos:
Fluid percussion injury
Sleep fragmentation
Memory
Neuroinflammation
Mouse
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666354624000759
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