Detecting HER2-positive circulating tumor cells in gastric cancer using a flow cytometry-based approach

BackgroundHER2 overexpression predicts the response to trastuzumab in gastric cancer (GC); however, assessing this overexpression requires invasive immunohistochemistry. Circulating tumor cells (CTCs) share comparable proteomic phenotypes to those of the primary tumor and represent a less invasive m...

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Main Authors:	Jan-Mou Lee, Chia-Chun Tu, Chih-Hao Fang, Shian-Ren Lin, Shiu-Lan Wang, Wan-Yu Lai, Po-Wei Tseng, Wan-En Liao, Li-Yun Huang, Yee Chao, Ming-Huang Chen
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2025-09-01
Series:	Frontiers in Medicine
Subjects:	circulating tumor cells flow cytometry gastric cancer HER2 overexpression liquid biopsy
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1672955/full
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