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The role of PB1-F2 in adaptation of high pathogenicity avian influenza virus H7N7 in chickens

Abstract Avian influenza viruses (AIV) of the H7N7 subtype are enzootic in the wild bird reservoir in Europe, cause infections in poultry, and have sporadically infected humans. The non-structural protein PB1-F2 is encoded in a second open frame in the polymerase segment PB1 and its sequence varies...

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Hauptverfasser: Luise Hohensee, David Scheibner, Alexander Schäfer, Holly Shelton, Thomas C. Mettenleiter, Angele Breithaupt, Anca Dorhoi, Elsayed M. Abdelwhab, Ulrike Blohm
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-01-01
Schriftenreihe:Veterinary Research
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Online-Zugang:https://doi.org/10.1186/s13567-023-01257-8
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