Modeling interaction of Glioma cells and CAR T-cells considering multiple CAR T-cells bindings

Chimeric antigen receptor (CAR) T-cell based immunotherapy has shown its potential in treating blood cancers, and its application to solid tumors is currently being extensively investigated. For glioma brain tumors, various CAR T-cell targets include IL13Rα2, EGFRvIII, HER2, EphA2, GD2, B7-H3, and c...

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Principais autores:	Runpeng Li, Prativa Sahoo, Dongrui Wang, Qixuan Wang, Christine E. Brown, Russell C. Rockne, Heyrim Cho
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2023-03-01
Serija:	ImmunoInformatics
Teme:	Immunotherapy Adoptive cell therapy Chimeric antigen receptor T-cell Mathematical Oncology Dynamical system
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2667119023000022
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