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Role of NAT10-mediated ac4C acetylation of ENO1 mRNA in glycolysis and apoptosis in non-small cell lung cancer cells

Abstract Background Abnormal expression of N-acetyltransferase 10 (NAT10) has been shown to promote the progression of various tumors, including non-small cell lung cancer (NSCLC). This study was designed to investigate the role of NAT10 in NSCLC and the underlying mechanism. Methods Reverse transcr...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yanqing Yuan, Na Li, Jingui Zhu, Chun Shao, Xiangbo Zeng, Daijiao Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-02-01
Schriftenreihe:BMC Pulmonary Medicine
Schlagworte:
Non-small cell lung cancer
NAT10
ENO1
ac4C
Glycolysis
Apoptosis
Online-Zugang:https://doi.org/10.1186/s12890-024-03463-2
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