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Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo

Pre-messenger RNA splicing involves multi-step assembly of the large spliceosome complexes that catalyse the two consecutive trans-esterification reactions, resulting in intron removal. There is evidence that proof-reading mechanisms monitor the fidelity of this complex process. Transcripts that fai...

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Hlavní autoři: Gonzalo I. Mendoza-Ochoa, J. David Barrass, Isabella E. Maudlin, Jean D. Beggs
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2024-12-01
Edice:RNA Biology
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On-line přístup:https://www.tandfonline.com/doi/10.1080/15476286.2019.1657788
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