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Efficacy and safety of anti-CD38 monoclonal antibodies in patients with relapsed/refractory multiple myeloma: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials

ObjectivesThe current study aims to evaluate the safety and efficacy of anti-CD38 monoclonal antibodies (mAbs) among patients with relapsed/refractory multiple myeloma (RRMM) through meta-analysis.MethodsAs of June 2023, we searched PubMed, Web of Science, Embase and the Cochrane Library. Randomized...

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Principais autores: Lu Ye, Fei Zhou, Dongdong Cheng, Ming Xie, Xiaoli Yan, Yuyu Xue, Qian Yang, Rong Jia, Lili Zhong, Li Yang, Liqun Zou, Na Huang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-12-01
coleção:Frontiers in Oncology
Assuntos:
relapsed/refractory multiple myeloma
CD38
monoclonal antibodies
daratumumab
isatuximab
meta-analysis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2023.1240318/full
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