Broad T Cell Targeting of Structural Proteins After SARS-CoV-2 Infection: High Throughput Assessment of T Cell Reactivity Using an Automated Interferon Gamma Release Assay

BackgroundAdaptive immune responses to structural proteins of the virion play a crucial role in protection against coronavirus disease 2019 (COVID-19). We therefore studied T cell responses against multiple SARS-CoV-2 structural proteins in a large cohort using a simple, fast, and high-throughput ap...

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Egile Nagusiak:	Isabel Brand, Leonard Gilberg, Jan Bruger, Mercè Garí, Andreas Wieser, Tabea M. Eser, Jonathan Frese, Mohamed I. M. Ahmed, Raquel Rubio-Acero, Jessica M. Guggenbuehl Noller, Noemi Castelletti, Jana Diekmannshemke, Sophie Thiesbrummel, Duc Huynh, Simon Winter, Inge Kroidl, Christiane Fuchs, Michael Hoelscher, Julia Roider, Sebastian Kobold, Michael Pritsch, Christof Geldmacher
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2021-05-01
Saila:	Frontiers in Immunology
Gaiak:	SARS-CoV-2 COVID-19 T cell response interferon gamma release assay (IGRA) high through put
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.688436/full
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