Transfer of Synthetic Human Chromosome into Human Induced Pluripotent Stem Cells for Biomedical Applications

Alphoid^tetO-type human artificial chromosome (HAC) has been recently synthetized as a novel class of gene delivery vectors for induced pluripotent stem cell (iPSC)-based tissue replacement therapeutic approach. This HAC vector was designed to deliver copies of genes into patients with gen...

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Autors principals:	Sergey A. Sinenko, Elena V. Skvortsova, Mikhail A. Liskovykh, Sergey V. Ponomartsev, Andrey A. Kuzmin, Aleksandr A. Khudiakov, Anna B. Malashicheva, Natalia Alenina, Vladimir Larionov, Natalay Kouprina, Alexey N. Tomilin
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2018-12-01
Col·lecció:	Cells
Matèries:	human artificial chromosome (HAC) alphoid<sup>tetO</sup>-HAC induced pluripotent stem cells (iPSCs) microcell-mediated chromosome transfer (MMCT) cell reprogramming
Accés en línia:	https://www.mdpi.com/2073-4409/7/12/261
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