Hot-Melt Extrusion-Based Dexamethasone–PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation

Developing bioequivalent (BE) generic products of complex dosage forms like intravitreal implants (IVIs) of corticosteroids such as dexamethasone prepared using hot-melt extrusion (HME), based on biodegradable poly (lactide-co-glycolide) (PLGA) polymers, can be challenging. A better understanding of...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Alireza (Allen) Ghaffari, Brock A. Matter, Rachel R. Hartman, David W. A. Bourne, Yan Wang, Stephanie Choi, Uday B. Kompella
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2024-07-01
Sarja:	Pharmaceutics
Aiheet:	biodegradable corticosteroid dexamethasone hot-melt extrusion (HME) LC-MS/MS intravitreal
Linkit:	https://www.mdpi.com/1999-4923/16/7/895
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