Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative splicing

Abstract Prostate cancer (PCa) is the most prevalent type of cancer and the second leading cause of mortality in males, with a marked increase in incidence observed across the globe. In the present study, whole-transcriptome analysis was conducted to identify differentially expressed circular RNAs (...

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Hlavní autoři:	Jianfeng Li, Hui Qiu, Qingzhuo Dong, Hongyuan Yu, Chiyuan Piao, Zhengxiu Li, Yanbin Sun, Xiaolu Cui
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2024-11-01
Edice:	Cell Death and Disease
On-line přístup:	https://doi.org/10.1038/s41419-024-07246-9
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