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Modular reconstruction and optimization of the trans-4-hydroxy-L-proline synthesis pathway in Escherichia coli

Abstract Background In recent years, there has been a growing demand for microbial production of trans-4-hydroxy-L-proline (t4Hyp), which is a value-added amino acid and has been widely used in the fields of medicine, food, and cosmetics. In this study, a multivariate modular metabolic engineering a...

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主要な著者: Zhenyu Zhang, Weike Su, Yunyun Bao, Qianqian Huang, Kai Ye, Pengfu Liu, Xiaohe Chu
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2022-08-01
シリーズ:Microbial Cell Factories
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オンライン・アクセス:https://doi.org/10.1186/s12934-022-01884-4
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