Targeting BATF2-RGS2 axis reduces T-cell exhaustion and restores anti-tumor immunity
Abstract Objective This study aims to investigate the role of RGS2 in immune regulation in lung cancer (LC) and explore the regulatory relationship between RGS2 and BATF2 in modulating T cell exhaustion and tumor immune evasion. Methods Single-cell transcriptome-based analysis was performed to ident...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2025-05-01
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| シリーズ: | Molecular Cancer |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s12943-025-02351-5 |
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